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Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

Dicer is a large multi-domain protein responsible for the ultimate step of microRNA and short-interfering RNA biogenesis. In human and mouse cell lines, Dicer has been shown to be important in the nuclear clearance of dsRNA as well as the establishment of chromatin modifications. Here we set out to...

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Detalles Bibliográficos
Autores principales: Much, Christian, Auchynnikava, Tania, Pavlinic, Dinko, Buness, Andreas, Rappsilber, Juri, Benes, Vladimir, Allshire, Robin, O’Carroll, Dónal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890738/
https://www.ncbi.nlm.nih.gov/pubmed/27254021
http://dx.doi.org/10.1371/journal.pgen.1006095