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Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

INTRODUCTION: Currently available clinical assays to detect antiphospholipid antibodies (aPL) test for IgG and IgM antibodies to cardiolipin (aCL) and β(2)-glycoprotein I (aβ(2)GPI). It has been suggested that testing for IgA aPL and for antibodies to Domain I (DI), which carries the key antigenic e...

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Detalles Bibliográficos
Autores principales: Pericleous, Charis, Ferreira, Isabel, Borghi, Orietta, Pregnolato, Francesca, McDonnell, Thomas, Garza-Garcia, Acely, Driscoll, Paul, Pierangeli, Silvia, Isenberg, David, Ioannou, Yiannis, Giles, Ian, Meroni, Pier Luigi, Rahman, Anisur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890741/
https://www.ncbi.nlm.nih.gov/pubmed/27253369
http://dx.doi.org/10.1371/journal.pone.0156407