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Theoretical Insights into the Biophysics of Protein Bi-stability and Evolutionary Switches
Deciphering the effects of nonsynonymous mutations on protein structure is central to many areas of biomedical research and is of fundamental importance to the study of molecular evolution. Much of the investigation of protein evolution has focused on mutations that leave a protein’s folded structur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890782/ https://www.ncbi.nlm.nih.gov/pubmed/27253392 http://dx.doi.org/10.1371/journal.pcbi.1004960 |