MGMT Promoter Methylation and BRAF V600E Mutations Are Helpful Markers to Discriminate Pleomorphic Xanthoastrocytoma from Giant Cell Glioblastoma

Giant Cell Glioblastoma (gcGBM) and Pleomorphic Xanthoastrocytoma (PXA) are rare astroglial tumors of the central nervous system. Although they share certain histomorphological and immunohistochemical features, they are characterized by different clinical behavior and prognosis. Nevertheless, few ca...

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Detalles Bibliográficos
Autores principales: Lohkamp, Laura-Nanna, Schinz, Maren, Gehlhaar, Claire, Guse, Katrin, Thomale, Ulrich-Wilhelm, Vajkoczy, Peter, Heppner, Frank L., Koch, Arend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890800/
https://www.ncbi.nlm.nih.gov/pubmed/27253461
http://dx.doi.org/10.1371/journal.pone.0156422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890800/
https://www.ncbi.nlm.nih.gov/pubmed/27253461
http://dx.doi.org/10.1371/journal.pone.0156422

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