Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound

In staphylococci, quorum sensing regulates both biofilm formation and toxin production, moreover it has been demonstrated to be inhibited by RNAIII inhibiting peptide (RIP). Aim our study was to evaluate the in vitro activity and its in vivo efficacy of the combined administration of FS10, a novel R...

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Detalles Bibliográficos
Autores principales: Simonetti, Oriana, Cirioni, Oscar, Cacciatore, Ivana, Baldassarre, Leonardo, Orlando, Fiorenza, Pierpaoli, Elisa, Lucarini, Guendalina, Orsetti, Elena, Provinciali, Mauro, Fornasari, Erika, Di Stefano, Antonio, Giacometti, Andrea, Offidani, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890846/
https://www.ncbi.nlm.nih.gov/pubmed/27253706
http://dx.doi.org/10.1371/journal.pone.0151956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890846/
https://www.ncbi.nlm.nih.gov/pubmed/27253706
http://dx.doi.org/10.1371/journal.pone.0151956

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