Receptor Binding by Cholera Toxin B-Subunit and Amino Acid Modification Improves Minimal Peptide Immunogenicity

We increase our understanding of augmenting a cellular immune response, by using an HIV-1 protease-derived epitope (PR(75–84)), and variants thereof, coupled to the C-terminal, of the B subunit of cholera toxin (CTB). Fusion proteins were used for immunizations of HLA-A0201 transgenic C57BL/6 mice....

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Detalles Bibliográficos
Autores principales: Boberg, Andreas, Stålnacke, Alexandra, Bråve, Andreas, Hinkula, Jorma, Wahren, Britta, Carlin, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890861/
https://www.ncbi.nlm.nih.gov/pubmed/27335661
http://dx.doi.org/10.5402/2012/170676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890861/
https://www.ncbi.nlm.nih.gov/pubmed/27335661
http://dx.doi.org/10.5402/2012/170676

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