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Receptor Binding by Cholera Toxin B-Subunit and Amino Acid Modification Improves Minimal Peptide Immunogenicity
We increase our understanding of augmenting a cellular immune response, by using an HIV-1 protease-derived epitope (PR(75–84)), and variants thereof, coupled to the C-terminal, of the B subunit of cholera toxin (CTB). Fusion proteins were used for immunizations of HLA-A0201 transgenic C57BL/6 mice....
Autores principales: | Boberg, Andreas, Stålnacke, Alexandra, Bråve, Andreas, Hinkula, Jorma, Wahren, Britta, Carlin, Nils |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890861/ https://www.ncbi.nlm.nih.gov/pubmed/27335661 http://dx.doi.org/10.5402/2012/170676 |
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