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Evolution-Based Functional Decomposition of Proteins

The essential biological properties of proteins—folding, biochemical activities, and the capacity to adapt—arise from the global pattern of interactions between amino acid residues. The statistical coupling analysis (SCA) is an approach to defining this pattern that involves the study of amino acid...

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Detalles Bibliográficos
Autores principales: Rivoire, Olivier, Reynolds, Kimberly A., Ranganathan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890866/
https://www.ncbi.nlm.nih.gov/pubmed/27254668
http://dx.doi.org/10.1371/journal.pcbi.1004817