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Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration

The disruption of retinal pigment epithelial (RPE) function and the degeneration of photoreceptors are cardinal features of age related macular degeneration (AMD); however there are still gaps in our understanding of underlying biological processes. Excess homocysteine (Hcy) has been reported to be...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ahmed S., Mander, Suchreet, Hussein, Khaled A., Elsherbiny, Nehal M., Smith, Sylvia B., Al-Shabrawey, Mohamed, Tawfik, Amany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890985/
https://www.ncbi.nlm.nih.gov/pubmed/26885895
http://dx.doi.org/10.18632/oncotarget.7384