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GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis

The glucocorticoid-induced TNFR family-related protein (GITR) and its ligand play a critical role in the pathogenesis of autoimmune arthritis by enhancing the Th17 cell response, but their molecular mechanisms remain largely unclear. This study aims to define the role of p38 mitogen-activated protei...

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Detalles Bibliográficos
Autores principales: Tang, Xinyi, Tian, Jie, Ma, Jie, Wang, Jiemin, Qi, Chen, Rui, Ke, Wang, Yungang, Xu, Huaxi, Lu, Liwei, Wang, Shengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890989/
https://www.ncbi.nlm.nih.gov/pubmed/26657118
http://dx.doi.org/10.18632/oncotarget.6535