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GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis
The glucocorticoid-induced TNFR family-related protein (GITR) and its ligand play a critical role in the pathogenesis of autoimmune arthritis by enhancing the Th17 cell response, but their molecular mechanisms remain largely unclear. This study aims to define the role of p38 mitogen-activated protei...
Autores principales: | Tang, Xinyi, Tian, Jie, Ma, Jie, Wang, Jiemin, Qi, Chen, Rui, Ke, Wang, Yungang, Xu, Huaxi, Lu, Liwei, Wang, Shengjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890989/ https://www.ncbi.nlm.nih.gov/pubmed/26657118 http://dx.doi.org/10.18632/oncotarget.6535 |
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