Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters

The transcription factor CREB (cAMP Response Element Binding Protein) is an important determinant in the growth of Acute Myeloid Leukemia (AML) cells. CREB overexpression increases AML cell growth by driving the expression of key regulators of apoptosis and the cell cycle. Conversely, CREB knockdown...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitton, Bryan, Hsu, Katie, Dutta, Ritika, Tiu, Bruce C., Cox, Nick, McLure, Kevin G., Chae, Hee-Don, Smith, Mark, Eklund, Elizabeth A., Solow-Cordero, David E., Sakamoto, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890994/
https://www.ncbi.nlm.nih.gov/pubmed/26840025
http://dx.doi.org/10.18632/oncotarget.7085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890994/
https://www.ncbi.nlm.nih.gov/pubmed/26840025
http://dx.doi.org/10.18632/oncotarget.7085

Ejemplares similares