TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas

Increasing evidences have implicated somatic gain-of-function mutations at the telomerase reverse transcriptase (TERT) promoter as one of the major mechanisms that promote transcriptional activation of TERT and subsequently maintain telomere length in human cancers including glioma. To investigate t...

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Detalles Bibliográficos
Autores principales: Gao, Ke, Li, Gang, Qu, Yiping, Wang, Maode, Cui, Bo, Ji, Meiju, Shi, Bingyin, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890999/
https://www.ncbi.nlm.nih.gov/pubmed/26556853
http://dx.doi.org/10.18632/oncotarget.6007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890999/
https://www.ncbi.nlm.nih.gov/pubmed/26556853
http://dx.doi.org/10.18632/oncotarget.6007

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