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An individualized prognostic signature for gastric cancer patients treated with 5-Fluorouracil-based chemotherapy and distinct multi-omics characteristics of prognostic groups

5-Fluorouracil (5-FU)-based chemotherapy is currently the first-line treatment for gastric cancer. In this study, using gene expression profiles for a panel of cell lines with drug sensitivity data and two cohorts of patients, we extracted a signature consisting of two gene pairs (KCNE2 and API5, KC...

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Detalles Bibliográficos
Autores principales: Li, Xiangyu, Cai, Hao, Zheng, Weicheng, Tong, Mengsha, Li, Hongdong, Ao, Lu, Li, Jing, Hong, Guini, Li, Mengyao, Guan, Qingzhou, Yang, Sheng, Yang, Da, Lin, Xu, Guo, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891001/
https://www.ncbi.nlm.nih.gov/pubmed/26840027
http://dx.doi.org/10.18632/oncotarget.7087