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Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2

Hepatic stellate cells (HSCs) are critical mediators of immunosuppression and the pathogenesis of hepatocellular carcinoma (HCC). Our previous work indicates that HSCs promote HCC progression by enhancing immunosuppressive cell populations including myeloid-derived suppressor cells (MDSCs) and regul...

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Detalles Bibliográficos
Autores principales: Xu, Yaping, Zhao, Wenxiu, Xu, Jianfeng, Li, Jie, Hong, Zaifa, Yin, Zhenyu, Wang, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891010/
https://www.ncbi.nlm.nih.gov/pubmed/26758420
http://dx.doi.org/10.18632/oncotarget.6839