Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation

PTEN loss and PIK3CA activation both promote the accumulation of phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3). While these proteins also have distinct biochemical functions, beyond the regulation of PIP3, little is known about the consequences of these differences in vivo. Here, we directly c...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jeff C., Wang, Dong-Yu, Egan, Sean E., Zacksenhaus, Eldad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891026/
https://www.ncbi.nlm.nih.gov/pubmed/26814435
http://dx.doi.org/10.18632/oncotarget.6985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891026/
https://www.ncbi.nlm.nih.gov/pubmed/26814435
http://dx.doi.org/10.18632/oncotarget.6985

Ejemplares similares