Cargando…
Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation
PTEN loss and PIK3CA activation both promote the accumulation of phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3). While these proteins also have distinct biochemical functions, beyond the regulation of PIP3, little is known about the consequences of these differences in vivo. Here, we directly c...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891026/ https://www.ncbi.nlm.nih.gov/pubmed/26814435 http://dx.doi.org/10.18632/oncotarget.6985 |