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Cold inducible RNA binding protein upregulation in pituitary corticotroph adenoma induces corticotroph cell proliferation via Erk signaling pathway

Cushing's disease is caused by pituitary corticotroph adenoma, and the pathogenesis of it has remained obscure. Here, we showed that cold inducible RNA binding protein (CIRP) was markedly elevated in corticotroph tumors. Forced overexpression of CIRP in murine AtT20 pituitary corticotroph cell...

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Detalles Bibliográficos
Autores principales: Jian, Fangfang, Chen, Yufan, Ning, Guang, Fu, Wei, Tang, Hao, Chen, Xiao, Zhao, Yao, Zheng, Lili, Pan, Sijian, Wang, Weiqing, Bian, Liuguan, Sun, Qingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891034/
https://www.ncbi.nlm.nih.gov/pubmed/26824322
http://dx.doi.org/10.18632/oncotarget.7037