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BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells

Autophagy is the basic catabolic mechanism that involves cell degradation of unnecessary or dysfunctional cellular components. Autophagy has a controversial role in cancer – both in protecting against tumor progression by isolation of damaged organelles, or by potentially contributing to cancer grow...

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Detalles Bibliográficos
Autores principales: Goulielmaki, Maria, Koustas, Evangelos, Moysidou, Eirini, Vlassi, Margarita, Sasazuki, Takehiko, Shirasawa, Senji, Zografos, George, Oikonomou, Eftychia, Pintzas, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891035/
https://www.ncbi.nlm.nih.gov/pubmed/26802026
http://dx.doi.org/10.18632/oncotarget.6942