A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function

In cancer cells, failure of chemotherapy is often caused by the ATP-binding cassette subfamily B member 1 (ABCB1), and few drugs have been successfully developed to overcome ABCB1-mediated multi-drug resistance (MDR). To suppress ABCB1 activity, we previously designed and synthesized a new series of...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Gang, Liu, Junhua, Chen, Wantao, Xu, Qin, Xiao, Meng, Hu, Lihong, Mao, Li, Wang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891047/
https://www.ncbi.nlm.nih.gov/pubmed/26824187
http://dx.doi.org/10.18632/oncotarget.7011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891047/
https://www.ncbi.nlm.nih.gov/pubmed/26824187
http://dx.doi.org/10.18632/oncotarget.7011

Ejemplares similares