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A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function

In cancer cells, failure of chemotherapy is often caused by the ATP-binding cassette subfamily B member 1 (ABCB1), and few drugs have been successfully developed to overcome ABCB1-mediated multi-drug resistance (MDR). To suppress ABCB1 activity, we previously designed and synthesized a new series of...

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Detalles Bibliográficos
Autores principales:	Chen, Gang, Liu, Junhua, Chen, Wantao, Xu, Qin, Xiao, Meng, Hu, Lihong, Mao, Li, Wang, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891047/ https://www.ncbi.nlm.nih.gov/pubmed/26824187 http://dx.doi.org/10.18632/oncotarget.7011

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