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A TET2 rs3733609 C/T genotype is associated with predisposition to the myeloproliferative neoplasms harboring JAK2(V617F) and confers a proliferative potential on erythroid lineages

Common germline single-nucleotide polymorphisms (SNPs) at JAK2 locus have been associated with Myeloproliferative neoplasms (MPN). And, the germline sequence variant rs2736100 C in TERT is related to risk of MPN, suggesting a complex association between SNPs and the pathogenesis of MPN. Our previous...

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Detalles Bibliográficos
Autores principales: Shen, Xiao-hui, Sun, Nan-nan, Yin, Ya-fei, Liu, Su-fang, Liu, Xiao-liu, Peng, Hong-ling, Dai, Chong-wen, Xu, Yun-xiao, Deng, Ming-yang, Luo, Yun-ya, Zheng, Wen-li, Zhang, Guang-sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891059/
https://www.ncbi.nlm.nih.gov/pubmed/26843622
http://dx.doi.org/10.18632/oncotarget.7072