Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients

Germline mutations in BRCA1 and BRCA2 are the most penetrating genetic predispositions for breast and ovarian cancer, and their presence is largely ethnic-specific. Comprehensive information about the prevalence and spectrum of BRCA mutations has been collected in European and North American populat...

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Detalles Bibliográficos
Autores principales: Kim, Yeong C., Zhao, Linli, Zhang, Hanwen, Huang, Ye, Cui, Jian, Xiao, Fengxia, Downs, Bradley, Wang, San Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891063/
https://www.ncbi.nlm.nih.gov/pubmed/26848529
http://dx.doi.org/10.18632/oncotarget.7144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891063/
https://www.ncbi.nlm.nih.gov/pubmed/26848529
http://dx.doi.org/10.18632/oncotarget.7144

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