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Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

Spliceosome mutations are frequently observed in patients with myelodysplastic syndromes (MDS). However, it is largely unknown how these mutations contribute to the disease. MicroRNAs (miRNAs) are small noncoding RNAs, which have been implicated in most human cancers due to their role in post transc...

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Detalles Bibliográficos
Autores principales: Aslan, Derya, Garde, Christian, Nygaard, Mette Katrine, Helbo, Alexandra Søgaard, Dimopoulos, Konstantinos, Hansen, Jakob Werner, Severinsen, Marianne Tang, Treppendahl, Marianne Bach, Sjø, Lene Dissing, Grønbæk, Kirsten, Kristensen, Lasse Sommer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891095/
https://www.ncbi.nlm.nih.gov/pubmed/26848861
http://dx.doi.org/10.18632/oncotarget.7127