The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells

Growth arrest-specific 5 (GAS5) lncRNA promotes apoptosis, and its expression is down-regulated in breast cancer. GAS5 lncRNA is a decoy of glucocorticoid/related receptors; a stem-loop sequence constitutes the GAS5 hormone response element mimic (HREM), which is essential for the regulation of brea...

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Detalles Bibliográficos
Autores principales: Pickard, Mark R., Williams, Gwyn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891107/
https://www.ncbi.nlm.nih.gov/pubmed/26862727
http://dx.doi.org/10.18632/oncotarget.7173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891107/
https://www.ncbi.nlm.nih.gov/pubmed/26862727
http://dx.doi.org/10.18632/oncotarget.7173

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