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Ras-activated RSK1 phosphorylates EBP50 to regulate its nuclear localization and promote cell proliferation
Differential subcellular localization of EBP50 leads to its controversial role in cancer biology either as a tumor suppressor when it resides at the membrane periphery, or a tumor facilitator at the nucleus. However, the mechanism behind nuclear localization of EBP50 remains unclear. A RNA interfere...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891120/ https://www.ncbi.nlm.nih.gov/pubmed/26862730 http://dx.doi.org/10.18632/oncotarget.7184 |