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Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC

BACKGROUND PROMOTER: hypermethylation plays a major role in cancer through transcriptional silencing of critical genes. The aim of our study is to evaluate the methylation status of these genes in the colonic mucosa without dysplasia or adenocarcinoma at the different steps of sporadic and UC-relate...

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Detalles Bibliográficos
Autores principales: Scarpa, Marco, Scarpa, Melania, Castagliuolo, Ignazio, Erroi, Francesca, Kotsafti, Andromachi, Basato, Silvia, Brun, Paola, D'Incà, Renata, Rugge, Massimo, Angriman, Imerio, Castoro, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891122/
https://www.ncbi.nlm.nih.gov/pubmed/26862732
http://dx.doi.org/10.18632/oncotarget.7188