Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway

Statins (3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase inhibitors) are well-established agents to treat hyperlipidemic states. Experimental and epidemiological evidence further implies an anticancer effect of these substances. This study investigates the mechanism underlying human lung c...

Descripción completa

Detalles Bibliográficos
Autores principales: Walther, Udo, Emmrich, Kristin, Ramer, Robert, Mittag, Nadine, Hinz, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891124/
https://www.ncbi.nlm.nih.gov/pubmed/26863638
http://dx.doi.org/10.18632/oncotarget.7213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891124/
https://www.ncbi.nlm.nih.gov/pubmed/26863638
http://dx.doi.org/10.18632/oncotarget.7213

Ejemplares similares