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Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway

Progestin resistance is a main obstacle for endometrial precancer/cancer conservative therapy. Therefore, biomarkers to predict progestin resistance and studies to gain a more detailed understanding of the mechanism are needed. The antioxidant Nrf2-AKR1C1 signal pathway exerts chemopreventive activi...

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Detalles Bibliográficos
Autores principales: Wang, Yiying, Wang, Yue, Zhang, Zhenbo, Park, Ji-Young, Guo, Donghui, Liao, Hong, Yi, Xiaofang, Zheng, Yu, Zhang, Donna, Chambers, Setsuko K., Zheng, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891125/
https://www.ncbi.nlm.nih.gov/pubmed/26824415
http://dx.doi.org/10.18632/oncotarget.7004