Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

Targeted delivery of anticancer drugs to tumor cells using monoclonal antibodies against oncogenic cell surface receptors is an emerging therapeutic strategy. These strategies include drugs directly conjugated to monoclonal antibodies through chemical linkers (Antibody-Drug Conjugates, ADCs) or thos...

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Detalles Bibliográficos
Autores principales: Raja, Srikumar M., Desale, Swapnil S., Mohapatra, Bhopal, Luan, Haitao, Soni, Kruti, Zhang, Jinjin, Storck, Matthew A., Feng, Dan, Bielecki, Timothy A., Band, Vimla, Cohen, Samuel M., Bronich, Tatiana K., Band, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891137/
https://www.ncbi.nlm.nih.gov/pubmed/26859680
http://dx.doi.org/10.18632/oncotarget.7231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891137/
https://www.ncbi.nlm.nih.gov/pubmed/26859680
http://dx.doi.org/10.18632/oncotarget.7231

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