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Heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by increasing protein translation of selected transcripts in cancer cells

The heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by coordinating the translation of selected transcripts associated with proliferation and survival. hnRNP A18 binds to and stabilizes the transcripts of pro-survival genes harboring its RNA signature motif in their 3′UTRs. hnRN...

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Detalles Bibliográficos
Autores principales: Chang, Elizabeth T., Parekh, Palak R., Yang, Qingyuan, Nguyen, Duc M., Carrier, France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891142/
https://www.ncbi.nlm.nih.gov/pubmed/26824423
http://dx.doi.org/10.18632/oncotarget.7020