Construction of a new anti-CD19 chimeric antigen receptor and the anti-leukemia function study of the transduced T cells

Chimeric antigen receptor (CAR) transduced T cells have been used to efficiently kill the target tumor cells depending on the single chain variable fragment (scFv) against the specific tumor associated antigen. Here we show the high specific cytotoxicity of the CAR-T cells with very low effector to...

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Detalles Bibliográficos
Autores principales: An, Na, Tao, Zhongfei, Li, Saisai, Xing, Haiyan, Tang, Kejing, Tian, Zheng, Rao, Qing, Wang, Min, Wang, Jianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891147/
https://www.ncbi.nlm.nih.gov/pubmed/26840021
http://dx.doi.org/10.18632/oncotarget.7079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891147/
https://www.ncbi.nlm.nih.gov/pubmed/26840021
http://dx.doi.org/10.18632/oncotarget.7079

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