Ultrasound-targeted hepatic delivery of factor IX in hemophiliac mice

Ultrasound-targeted microbubble destruction (UTMD) was used to direct the delivery of plasmid and transposase-based vectors encoding human factor IX (hFIX) to the livers of hemophilia B (FIX−/−) mice. The DNA vectors were incorporated into cationic lipid microbubbles, injected intravenously, and tra...

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Detalles Bibliográficos
Autores principales: Anderson, C D, Moisyadi, S, Avelar, A, Walton, C B, Shohet, R V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891223/
https://www.ncbi.nlm.nih.gov/pubmed/26960037
http://dx.doi.org/10.1038/gt.2016.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891223/
https://www.ncbi.nlm.nih.gov/pubmed/26960037
http://dx.doi.org/10.1038/gt.2016.23

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