Context-dependent effects of cellular senescence in cancer development

Cellular senescence is an established tumour-suppressive mechanism that prevents the proliferation of premalignant cells. However, several lines of evidence show that senescent cells, which often persist in vivo, can also promote tumour progression in addition to other age-related pathologies via th...

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Detalles Bibliográficos
Autores principales: Lecot, Pacome, Alimirah, Fatouma, Desprez, Pierre-Yves, Campisi, Judith, Wiley, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891501/
https://www.ncbi.nlm.nih.gov/pubmed/27140310
http://dx.doi.org/10.1038/bjc.2016.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891501/
https://www.ncbi.nlm.nih.gov/pubmed/27140310
http://dx.doi.org/10.1038/bjc.2016.115

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