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Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology

The discovery of Th17 cell plasticity, in which CD4(+) IL-17–producing Th17 cells give rise to IL-17/IFN-γ double-producing cells and Th1-like IFNγ(+) ex-Th17 lymphocytes, has raised questions regarding which of these cell types contribute to immunopathology during inflammatory diseases. In this stu...

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Detalles Bibliográficos
Autores principales: Brucklacher-Waldert, Verena, Ferreira, Cristina, Innocentin, Silvia, Kamdar, Shraddha, Withers, David R., Kullberg, Marika C., Veldhoen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891569/
https://www.ncbi.nlm.nih.gov/pubmed/27183623
http://dx.doi.org/10.4049/jimmunol.1600137