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An autism-associated mutation in Ca(V)1.3 channels has opposing effects on voltage- and Ca(2+)-dependent regulation
Ca(V)1.3 channels are a major class of L-type Ca(2+) channels which contribute to the rhythmicity of the heart and brain. In the brain, these channels are vital for excitation-transcription coupling, synaptic plasticity, and neuronal firing. Moreover, disruption of Ca(V)1.3 function has been associa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891671/ https://www.ncbi.nlm.nih.gov/pubmed/27255217 http://dx.doi.org/10.1038/srep27235 |