Purifying selection shapes the coincident SNP distribution of primate coding sequences

Genome-wide analysis has observed an excess of coincident single nucleotide polymorphisms (coSNPs) at human-chimpanzee orthologous positions, and suggested that this is due to cryptic variation in the mutation rate. While this phenomenon primarily corresponds with non-coding coSNPs, the situation in...

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Detalles Bibliográficos
Autores principales: Chen, Chia-Ying, Hung, Li-Yuan, Wu, Chan-Shuo, Chuang, Trees-Juen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891680/
https://www.ncbi.nlm.nih.gov/pubmed/27255481
http://dx.doi.org/10.1038/srep27272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891680/
https://www.ncbi.nlm.nih.gov/pubmed/27255481
http://dx.doi.org/10.1038/srep27272

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