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CXCL3 contributes to CD133(+) CSCs maintenance and forms a positive feedback regulation loop with CD133 in HCC via Erk1/2 phosphorylation

Although the chemotactic cytokine CXCL3 is thought to play an important role in tumor initiation and invasion, little is known about its function in hepatocellular carcinoma (HCC). In our previous study, we found that Ikaros inhibited CD133 expression via the MAPK pathway in HCC. Here, we showed tha...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Zhang, Lixing, Li, Hong, Ge, Chao, Zhao, Fangyu, Tian, Hua, Chen, Taoyang, Jiang, Guoping, Xie, Haiyang, Cui, Ying, Yao, Ming, Li, Jinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891684/
https://www.ncbi.nlm.nih.gov/pubmed/27255419
http://dx.doi.org/10.1038/srep27426