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Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue

Overexpression of the ATP-dependent drug efflux pump ABCG2 is a major molecular mechanism of multidrug resistance in cancer and might be a predictive biomarker for drug response. Contradictory results have been reported for immunohistochemical studies of ABCG2 protein expression in colorectal cancer...

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Detalles Bibliográficos
Autores principales: Cederbye, Camilla Natasha, Palshof, Jesper Andreas, Hansen, Tine Plato, Duun-Henriksen, Anne Katrine, Linnemann, Dorte, Stenvang, Jan, Nielsen, Dorte Lisbet, Brünner, Nils, Viuff, Birgitte Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891695/
https://www.ncbi.nlm.nih.gov/pubmed/27257141
http://dx.doi.org/10.1038/srep26997