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Non-random distribution of homo-repeats: links with biological functions and human diseases

The biological function of multiple repetitions of single amino acids, or homo-repeats, is largely unknown, but their occurrence in proteins has been associated with more than 20 hereditary diseases. Analysing 122 bacterial and eukaryotic genomes, we observed that the number of proteins containing h...

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Detalles Bibliográficos
Autores principales: Lobanov, Michail Yu., Klus, Petr, Sokolovsky, Igor V., Tartaglia, Gian Gaetano, Galzitskaya, Oxana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891720/
https://www.ncbi.nlm.nih.gov/pubmed/27256590
http://dx.doi.org/10.1038/srep26941