Cargando…
Non-random distribution of homo-repeats: links with biological functions and human diseases
The biological function of multiple repetitions of single amino acids, or homo-repeats, is largely unknown, but their occurrence in proteins has been associated with more than 20 hereditary diseases. Analysing 122 bacterial and eukaryotic genomes, we observed that the number of proteins containing h...
Autores principales: | Lobanov, Michail Yu., Klus, Petr, Sokolovsky, Igor V., Tartaglia, Gian Gaetano, Galzitskaya, Oxana V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891720/ https://www.ncbi.nlm.nih.gov/pubmed/27256590 http://dx.doi.org/10.1038/srep26941 |
Ejemplares similares
-
HRaP: database of occurrence of HomoRepeats and patterns in proteomes
por: Lobanov, Mikhail Yu., et al.
Publicado: (2014) -
Proteome-scale understanding of relationship between homo-repeat enrichments and protein aggregation properties
por: Galzitskaya, Oxana V., et al.
Publicado: (2018) -
Disordered Patterns in Clustered Protein Data Bank and in Eukaryotic and Bacterial Proteomes
por: Lobanov, Michail Yu., et al.
Publicado: (2011) -
Repeats in S1 Proteins: Flexibility and Tendency for Intrinsic Disorder
por: Machulin, Andrey, et al.
Publicado: (2019) -
Neurodegeneration and Cancer: Where the Disorder Prevails
por: Klus, Petr, et al.
Publicado: (2015)