T cells expressing CD19-specific Engager Molecules for the Immunotherapy of CD19-positive Malignancies

T cells expressing chimeric antigen receptors (CARs) or the infusion of bispecific T-cell engagers (BITEs) have shown antitumor activity in humans for CD19-positive malignancies. While BITEs redirect the large reservoir of resident T cells to tumors, CAR T cells rely on significant in vivo expansion...

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Detalles Bibliográficos
Autores principales: Velasquez, Mireya Paulina, Torres, David, Iwahori, Kota, Kakarla, Sunitha, Arber, Caroline, Rodriguez-Cruz, Tania, Szoor, Arpad, Bonifant, Challice L., Gerken, Claudia, Cooper, Laurence J. N., Song, Xiao-Tong, Gottschalk, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891739/
https://www.ncbi.nlm.nih.gov/pubmed/27255991
http://dx.doi.org/10.1038/srep27130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891739/
https://www.ncbi.nlm.nih.gov/pubmed/27255991
http://dx.doi.org/10.1038/srep27130

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