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Circulatory shear flow alters the viability and proliferation of circulating colon cancer cells

During cancer metastasis, circulating tumor cells constantly experience hemodynamic shear stress in the circulation. Cellular responses to shear stress including cell viability and proliferation thus play critical roles in cancer metastasis. Here, we developed a microfluidic approach to establish a...

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Detalles Bibliográficos
Autores principales: Fan, Rong, Emery, Travis, Zhang, Yongguo, Xia, Yuxuan, Sun, Jun, Wan, Jiandi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891768/
https://www.ncbi.nlm.nih.gov/pubmed/27255403
http://dx.doi.org/10.1038/srep27073