Excessive Activation of TGFβ by Spinal Instability Causes Vertebral Endplate Sclerosis

Narrowed intervertebral disc (IVD) space is a characteristic of IVD degeneration. EP sclerosis is associated with IVD, however the pathogenesis of EP hypertrophy is poorly understood. Here, we employed two spine instability mouse models to investigate temporal and spatial EP changes associated with...

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Detalles Bibliográficos
Autores principales: Bian, Qin, Jain, Amit, Xu, Xin, Kebaish, Khaled, Crane, Janet L., Zhang, Zhendong, Wan, Mei, Ma, Lei, Riley, Lee H., Sponseller, Paul D., Guo, X. Edward, Lu, Willian Weijia, Wang, Yongjun, Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891769/
https://www.ncbi.nlm.nih.gov/pubmed/27256073
http://dx.doi.org/10.1038/srep27093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891769/
https://www.ncbi.nlm.nih.gov/pubmed/27256073
http://dx.doi.org/10.1038/srep27093

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