TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis

Previous study showed that TIGAR (TP53-induced glycolysis and apoptosis regulator) protected ischemic brain injury via enhancing pentose phosphate pathway (PPP) flux and preserving mitochondria function. This study was aimed to study the role of TIGAR in cerebral preconditioning. The ischemic precon...

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Detalles Bibliográficos
Autores principales: Zhou, Jun-Hao, Zhang, Tong-Tong, Song, Dan-Dan, Xia, Yun-Fei, Qin, Zheng-Hong, Sheng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891774/
https://www.ncbi.nlm.nih.gov/pubmed/27256465
http://dx.doi.org/10.1038/srep27096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891774/
https://www.ncbi.nlm.nih.gov/pubmed/27256465
http://dx.doi.org/10.1038/srep27096

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