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Programmed cell death-1 blockade in recurrent disseminated Ewing sarcoma

BACKGROUND: Ewing sarcoma (EWS) is a malignant tumour of bone and soft tissue, and although many patients are cured with conventional multimodal therapy, those with recurrent or metastatic disease have a poor prognosis. Genomic instability and programmed cell death ligand-1 (PD-L1) expression have b...

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Detalles Bibliográficos
Autores principales: McCaughan, Georgia J. B., Fulham, Michael J., Mahar, Annabelle, Soper, Judy, Hong, Angela M., Stalley, Paul D., Tattersall, Martin H. N., Bhadri, Vivek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891829/
https://www.ncbi.nlm.nih.gov/pubmed/27259563
http://dx.doi.org/10.1186/s13045-016-0278-x