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Are the physicochemical properties of antibacterial compounds really different from other drugs?

BACKGROUND: It is now widely recognized that there is an urgent need for new antibacterial drugs, with novel mechanisms of action, to combat the rise of multi-drug resistant bacteria. However, few new compounds are reaching the market. Antibacterial drug discovery projects often succeed in identifyi...

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Detalles Bibliográficos
Autores principales: Ebejer, Jean-Paul, Charlton, Michael H., Finn, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891840/
https://www.ncbi.nlm.nih.gov/pubmed/27274770
http://dx.doi.org/10.1186/s13321-016-0143-5