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Statistical inference of a convergent antibody repertoire response to influenza vaccine

BACKGROUND: Vaccines dramatically affect an individual’s adaptive immune system and thus provide an excellent means to study human immunity. Upon vaccination, the B cells that express antibodies (Abs) that happen to bind the vaccine are stimulated to proliferate and undergo mutagenesis at their Ab l...

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Detalles Bibliográficos
Autores principales: Strauli, Nicolas B., Hernandez, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891843/
https://www.ncbi.nlm.nih.gov/pubmed/27255379
http://dx.doi.org/10.1186/s13073-016-0314-z