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High-risk oral leukoplakia is associated with aberrant promoter methylation of multiple genes

BACKGROUND: Early detection of oral squamous cell carcinomas (OSCCs) is urgently needed to improve the prognosis and quality of life (QOL) of patients. Oral leukoplakias (OLs), known as the most common premalignant lesions in the oral cavity, often precede OSCCs. Especially, OLs with dysplasia are k...

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Detalles Bibliográficos
Autores principales: Abe, Masanobu, Yamashita, Satoshi, Mori, Yoshiyuki, Abe, Takahiro, Saijo, Hideto, Hoshi, Kazuto, Ushijima, Toshikazu, Takato, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891845/
https://www.ncbi.nlm.nih.gov/pubmed/27255271
http://dx.doi.org/10.1186/s12885-016-2371-5