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Protective role for miR-9-5p in the fibrogenic transformation of human dermal fibroblasts
BACKGROUND: Excessive accumulation of extracellular matrix (ECM) proteins is the hallmark of fibrotic diseases, including skin fibrosis. This response relies on the activation of dermal fibroblasts that evolve into a pro-fibrogenic phenotype. One of the major players in this process is the cytokine...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891847/ https://www.ncbi.nlm.nih.gov/pubmed/27274768 http://dx.doi.org/10.1186/s13069-016-0044-2 |