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Protective role for miR-9-5p in the fibrogenic transformation of human dermal fibroblasts

BACKGROUND: Excessive accumulation of extracellular matrix (ECM) proteins is the hallmark of fibrotic diseases, including skin fibrosis. This response relies on the activation of dermal fibroblasts that evolve into a pro-fibrogenic phenotype. One of the major players in this process is the cytokine...

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Detalles Bibliográficos
Autores principales: Miguel, Verónica, Busnadiego, Oscar, Fierro-Fernández, Marta, Lamas, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891847/
https://www.ncbi.nlm.nih.gov/pubmed/27274768
http://dx.doi.org/10.1186/s13069-016-0044-2